February 21, 2008

Protein In Deer Tick Saliva Prevents HIV-1 From Attaching To T Cells

The HIV-1 virus cripples the human immune system by targeting white blood cells called T cells that form the body’s first line of defense in fighting infections. A recent study shows that a protein found in the saliva of deer ticks prevents the HIV-1 virus from attaching to the surface of T cells, which is the critical first step in the virus’ attack strategy. Since the protein suppresses the action of T cells, it may also prove to be an effective treatment for autoimmune diseases like asthma and multiple sclerosis caused by an overactive immune system that mounts an attack against the body’s own cells and tissues, and it could be useful to suppress the immune system to prevent the rejection of transplanted organs.

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